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Pressure conduit system
The animal heart function research system is used to comprehensively evaluate animal heart function, including cardiac systolic and diastolic function
Product details
The animal cardiac function research system is used to comprehensively evaluate animal cardiac function, including cardiac systolic and diastolic function, pumping function, hemodynamics, cardiac electrophysiology, etc. It consists of an animal pressure measurement system, a ventricular pressure volume measurement system, and a cardiac electrophysiology measurement system. The three systems are independent of each other and are all composed of a Scisence solid-state catheter system and an iWorx data acquisition system.
Pressure conduit system
Scisense uses a solid-state pressure sensor, which is placed at the tip of a cardiac catheter. Through surgery, the catheter is placed in different positions on the body, such as the carotid artery, femoral artery, apex, bladder, etc., to directly detect changes in body pressure. Compared to traditional hydraulic conduits, it has high accuracy and good frequency response, and is highly favored by researchers.
The Scisense pressure conduit system consists of a main controller and pressure conduits, and suitable pressure conduits are selected according to different animal types.
SP200 type pressure main controller
ScisenseCharacteristics of pressure main controller
1. Can simultaneously connect two solid-state pressure conduits to measure two pressure signals
2. It has signal conditioning and amplification functions, without the need for additional amplifiers, with a pressure output accuracy of 22mV/mmHg
3. Strong compatibility, can be used with multiple brands of data acquisition analyzers, such as iWorx from the United States
4. LED displays pressure and voltage output signals, voltage output range:- 5 to+5 volts, pressure output range:- 100 to +
5. Two point pressure calibration balance method, electronic calibration is fast and accurate
6. Compatible with animals of different sizes such as rats, mice, guinea pigs, rabbits, cats, pigs, and dogs
Application scope: Measurement of various pressures such as arterial pressure, venous pressure, intracranial pressure, bladder pressure, urethral pressure, etc
Blood pressure measurement waveform diagram
ScisenseCharacteristics of pressure conduit
1. Polyimide conduit
·The catheter has appropriate softness and hardness, making it easy to insert into the heart for measurement
·Will not cause irritation or wear to the endothelium and valves of blood vessels
·The small caliber lumen entering the aorta has little impact on its blood flow and can obtain data that is closer to the physiological state
2. Smooth appearance
·Can reduce potential damage to vascular endothelium during intubation process
·Can make intubation easily pass through the aortic valve (able to repeatedly enter or exit)
·Can be reconstructed through arteries
3. High fidelity pressure sensor
·Has good high-frequency response, ensuring that the signal is not distorted or attenuated
·Unlike traditional liquid filled catheters, the Scisense catheter has no artifacts or extravasation phenomena
·The sensitivity is 10 μ/mmHg, and the measurement accuracy is higher than other similar products in the market
·The pressure sensor of the catheter is located in a small chamber recessed on the side of the catheter, which is not easily damaged
·Connected to the atmosphere for easy calibration of blood pressure monitors
·Can measure various chamber pressures such as vascular pressure, ventricular pressure, intracranial pressure, bladder pressure, urethral pressure, etc
Selection of pressure conduit model
| animal | Catheter model | Main applications and usage methods |
| mice | 1.2F single pressure conduit | Arterial or ventricular pressure measurement |
| 1.2F dual pressure conduit | Simultaneous measurement of carotid artery pressure and ventricular pressure | |
| rat | 1.6F single pressure conduit | Arterial or ventricular pressure measurement |
| 1.6F single pressure conduit | Simultaneous measurement of carotid artery pressure and ventricular pressure | |
| rabbit | 1.6F or 3.5F single pressure conduit | Arterial or ventricular pressure measurement |
| 3.5F dual pressure conduit | Simultaneous measurement of carotid artery pressure and ventricular pressure | |
| Large animals (Dogs, pigs, sheep) |
5.0F or 7.0F single pressure conduit (Roll Head) |
Arterial or ventricular pressure measurement can be inserted from the carotid or femoral artery |
| 5.0F or 7.0F single pressure conduit (Straight head) |
Arterial or ventricular pressure measurement, can be inserted from the apex of the heart during open chest surgery | |
| 5.0F or 7.0F dual pressure conduit (Roll Head) |
Simultaneous measurement of carotid and ventricular pressure, which can be inserted from the carotid or femoral artery | |
| 5.0F or 7.0F dual pressure conduit (Straight head) |
Simultaneous measurement of carotid artery pressure and ventricular pressure, allowing for open chest surgery with insertion from the apex of the heart |
LabScribeBlood pressure analysis module
1. Can simultaneously analyze arterial blood pressure and ventricular blood pressure data
2. It has specific analysis templates that can accurately depict the starting point, wave width, wave amplitude, etc. of each wave
3. Automatically depict the starting and ending points, wave width, etc. of each wave, and calculate parameters such as heart rate, systolic blood pressure, diastolic blood pressure, and ejection time
4. It is easy to extract source data or average data as images or text for export
5. Optional ASCII text import module to import BP data collected by other third-party devices into this software for analysis
LabScribe blood pressure analysis
Blood pressure analysis function parameters:
Arterial Pressure (AP): Heart Rate (HR), Maximum Pressure (Pmax), Minimum Pressure (Pmin), Mean Arterial Pressure (MAP), Systolic and Diastolic Pressure, Maximum dP/dt (dP/dtmax), Minimum dP/dt (dP/dtmin), Pulse Height, Notch Pressure, Systolic Duration, Diastolic Duration, Cycle Duration, Time To Peak, Election Time, Percent Recovery
Ventricular Pressure (LVP): Heart Rate (HR), Maximum Pressure (Pmax), Minimum Pressure (Pmin), Mean Pressure (Pmean), Endsystolic Pressure (Pes), Enddiastolic Pressure (Ped), Maximum dP/dt (dP/dtmax), Minimum dP/dt (dP/dtmin), Developed Pressure, dP/dt @, Contractility Index, Relaxation Index, Systolic Duration, Diastolic Duration, Cycle Duration, Tension Time Index, Relaxation Time, Isothermal Time, Tau (Weiss, Logistic) Glantz, Mirsky
reference:
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